About Gorlin Syndrome

About Gorlin Syndrome

Gorlin syndrome or Nevoid Basal Cell Carcinoma syndrome is a medical condition affecting many body systems and is caused by a fault in just one of the thousands of genes which humans possess. 

Read more: About Gorlin Syndrome

Features

There are many features which may occur in Gorlin Syndrome, although most are rare.   Some of the features are listed below.

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Skeletal

The Gorlin syndrome gene has an effect on the development of the skeletal system. This does not progress throughout life and usually causes no ill effects as all.

Read more: Skeletal

Jaw Cysts

The jaw cysts are known as keratocysts because they are filled with keratin, which is the material making up the outer layer of skin, hair and nails. 

Read more: Jaw Cysts

Basal Cell Carcinomas

90% of individuals with the syndrome will develop basal cell carcinomas (BCC) at some stage in their life.

Read more: Basal Cell Carcinomas


 Originally produced by Professor P. A. Farndon, Clinical Geneticist, Jim Costello (deceased) and Margaret Costello.  We are reliant on a team of medical advisors for the clinical content of the website. We are grateful for their continuing support. 
Gorlin Syndrome Group is Registered Charity in the UK - No 1096361 
 
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