The Gorlin Syndrome gene also has an afect on the development of the skeletal system. This does not progress throughout life and usually causes no ill effects as all.

The signs in the bones found in x-ray may be helpful in making progress.

Principally affected are the height, the shape of the ribs, the shape of the bones in the vertebral column, and the shape of the skull.

Height - people with Gorlin Syndrome can be much taller than expected for their family.

Shape and size of the skull is usually larger than average (usually over 60 cm in adults) - some people have difficulty in gettings hats. The front of the skull and the forehead may be very prominent, the bone being especially protruberant above and over the outer parts of the eyes (this is called 'frontal and parietal bossing'). A large proportion of babies with Gorlin Syndrome require delivery by Caesarian Section because of the large head size.